Quantitative Cervical Spinal Cord 3T Proton MR Spectroscopy in Multiple Sclerosis
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چکیده
منابع مشابه
Quantitative cervical spinal cord 3T proton MR spectroscopy in multiple sclerosis.
BACKGROUND AND PURPOSE Brain proton MR spectroscopy ((1)H-MR spectroscopy) is a useful technique for evaluating neuronal/axonal damage and demyelization in multiple sclerosis (MS). Because MS disability is frequently related to spinal cord lesions, potential markers for MS stage differentiation and severity would require in vivo quantification of spinal integrity. However, few spectroscopy stud...
متن کاملMR proton spectroscopy in multiple sclerosis.
PURPOSE To elucidate the natural history of visualized MR abnormalities in patients with multiple sclerosis using proton spectroscopy. METHODS MR imaging and proton spectroscopy (1H spectroscopy) were performed on 16 patients with clinically definite multiple sclerosis. All patients received gadopentetate dimeglumine (Gd-DTPA). RESULTS Decreased levels of N-acetylaspartate (NAA) were demons...
متن کاملA 3T MR imaging investigation of the topography of whole spinal cord atrophy in multiple sclerosis.
BACKGROUND AND PURPOSE Spinal cord atrophy is a common feature of MS. However, it is unknown which cord levels are most susceptible to atrophy. We performed whole cord imaging to identify the levels most susceptible to atrophy in patients with MS versus controls and also tested for differences among MS clinical phenotypes. MATERIALS AND METHODS Thirty-five patients with MS (2 with CIS, 27 wit...
متن کاملSpinal Cord Analysis in People with Multiple Sclerosis
Background. Multiple Sclerosis (MS) is an autoimmune, inflammatory, and chronic disease which, under the effect of the wastes of myelin degradation occurs in the white matter of the brain, spinal cord, and visual nerves. The main complications of this disease are fatigue, muscle cramps, tremor, imbalance, and walking imbalance. Objectives. The purpose of this study is to investigate the spine ...
متن کاملEvaluating single-point quantitative magnetization transfer in the cervical spinal cord: Application to multiple sclerosis
Spinal cord (SC) damage is linked to clinical deficits in patients with multiple sclerosis (MS), however, conventional MRI methods are not specific to the underlying macromolecular tissue changes that may precede overt lesion detection. Single-point quantitative magnetization transfer (qMT) is a method that can provide high-resolution indices sensitive to underlying macromolecular composition i...
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ژورنال
عنوان ژورنال: American Journal of Neuroradiology
سال: 2009
ISSN: 0195-6108,1936-959X
DOI: 10.3174/ajnr.a1738